From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Palmitoyltransferase ZDHHC17 is an enzyme that contains a DHHC domain that in humans is encoded by the ZDHHC17 gene .[ 5] [ 6] [ 7]
ZDHHC17 has been shown to interact with Huntingtin .[ 8] [ 9]
^ a b c GRCh38: Ensembl release 89: ENSG00000186908 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000035798 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Faber PW, Barnes GT, Srinidhi J, Chen J, Gusella JF, MacDonald ME (Sep 1998). "Huntingtin interacts with a family of WW domain proteins" . Human Molecular Genetics . 7 (9): 1463–74. doi :10.1093/hmg/7.9.1463 PMID 9700202 . ^ Goytain A, Hines RM, Quamme GA (Nov 2008). "Huntingtin-interacting proteins, HIP14 and HIP14L, mediate dual functions, palmitoyl acyltransferase and Mg2+ transport" . The Journal of Biological Chemistry . 283 (48): 33365–74. doi :10.1074/jbc.M801469200 PMC 2662264 PMID 18794299 . ^ "Entrez Gene: ZDHHC17 zinc finger, DHHC-type containing 17" .^ Faber PW, Barnes GT, Srinidhi J, Chen J, Gusella JF, MacDonald ME (Sep 1998). "Huntingtin interacts with a family of WW domain proteins" . Human Molecular Genetics . 7 (9): 1463–74. doi :10.1093/hmg/7.9.1463 PMID 9700202 . ^ Singaraja RR, Hadano S, Metzler M, Givan S, Wellington CL, Warby S, Yanai A, Gutekunst CA, Leavitt BR, Yi H, Fichter K, Gan L, McCutcheon K, Chopra V, Michel J, Hersch SM, Ikeda JE, Hayden MR (Nov 2002). "HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis" . Human Molecular Genetics . 11 (23): 2815–28. doi :10.1093/hmg/11.23.2815 PMID 12393793 .
Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Feb 1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro" . DNA Research . 6 (1): 63–70. doi :10.1093/dnares/6.1.63 PMID 10231032 . Singaraja RR, Hadano S, Metzler M, Givan S, Wellington CL, Warby S, Yanai A, Gutekunst CA, Leavitt BR, Yi H, Fichter K, Gan L, McCutcheon K, Chopra V, Michel J, Hersch SM, Ikeda JE, Hayden MR (Nov 2002). "HIP14, a novel ankyrin domain-containing protein, links huntingtin to intracellular trafficking and endocytosis" . Human Molecular Genetics . 11 (23): 2815–28. doi :10.1093/hmg/11.23.2815 PMID 12393793 . Matsuda A, Suzuki Y, Honda G, Muramatsu S, Matsuzaki O, Nagano Y, Doi T, Shimotohno K, Harada T, Nishida E, Hayashi H, Sugano S (May 2003). "Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways". Oncogene . 22 (21): 3307–18. doi :10.1038/sj.onc.1206406 . PMID 12761501 . S2CID 38880905 . Ducker CE, Stettler EM, French KJ, Upson JJ, Smith CD (Dec 2004). "Huntingtin interacting protein 14 is an oncogenic human protein: palmitoyl acyltransferase" . Oncogene . 23 (57): 9230–7. doi :10.1038/sj.onc.1208171 . PMC 2908390 PMID 15489887 . Huang K, Yanai A, Kang R, Arstikaitis P, Singaraja RR, Metzler M, Mullard A, Haigh B, Gauthier-Campbell C, Gutekunst CA, Hayden MR, El-Husseini A (Dec 2004). "Huntingtin-interacting protein HIP14 is a palmitoyl transferase involved in palmitoylation and trafficking of multiple neuronal proteins" . Neuron . 44 (6): 977–86. doi :10.1016/j.neuron.2004.11.027 PMID 15603740 . S2CID 14406733 .
