TAS2R43

TAS2R43
Identifiers
Aliases	TAS2R43, T2R43, T2R52, taste 2 receptor member 43
External IDs	OMIM: 612668; MGI: 2681304; HomoloGene: 128798; GeneCards: TAS2R43; OMA:TAS2R43 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	11,092,313 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	132,755,125 bp
RNA expression pattern
	Top expressed in
	testicle; ; muscle of thigh; ; tonsil; ; Achilles tendon; ; sural nerve; ; apex of heart; ; urinary bladder; ; ganglionic eminence; ; renal cortex; ; ectocervix;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; taste receptor activity; bitter taste receptor activity;
Cellular component	plasma membrane; cell projection; motile cilium; cilium; membrane; ciliary membrane; integral component of membrane;
Biological process	detection of chemical stimulus involved in sensory perception of bitter taste; signal transduction; response to stimulus; sensory perception of taste; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	259289
	353165
	ENSG00000255374; ENSG00000262612; ENSG00000282537
	ENSMUSG00000053217
	P59537
	Q7TQA8
	NM_176884
	NM_181276
	NP_795365
	NP_851793
	Wikidata
View/Edit Human	View/Edit Mouse

Taste receptor type 2 member 43 is a protein that in humans is encoded by the TAS2R43 gene.^[5]^[6]

References

^ ^a ^b ^c ENSG00000262612, ENSG00000282537 GRCh38: Ensembl release 89: ENSG00000255374, ENSG00000262612, ENSG00000282537 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000053217 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (Oct 2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat Genet. 32 (3): 397–401. doi:10.1038/ng1014. PMID 12379855. S2CID 20426192.
^ "Entrez Gene: TAS2R43 taste receptor, type 2, member 43".

Margolskee RF (2002). "Molecular mechanisms of bitter and sweet taste transduction". J. Biol. Chem. 277 (1): 1–4. doi:10.1074/jbc.R100054200. PMID 11696554.
Montmayeur JP, Matsunami H (2002). "Receptors for bitter and sweet taste". Curr. Opin. Neurobiol. 12 (4): 366–71. doi:10.1016/S0959-4388(02)00345-8. PMID 12139982. S2CID 37807140.
Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ (2003). "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways". Cell. 112 (3): 293–301. doi:10.1016/S0092-8674(03)00071-0. PMID 12581520. S2CID 718601.
Conte C, Ebeling M, Marcuz A, Nef P, Andres-Barquin PJ (2003). "Identification and characterization of human taste receptor genes belonging to the TAS2R family". Cytogenet. Genome Res. 98 (1): 45–53. doi:10.1159/000068546. PMID 12584440. S2CID 1542970.
Fischer A, Gilad Y, Man O, Pääbo S (2005). "Evolution of bitter taste receptors in humans and apes". Mol. Biol. Evol. 22 (3): 432–6. doi:10.1093/molbev/msi027. PMID 15496549.
Kuhn C, Bufe B, Winnig M, Hofmann T, Frank O, Behrens M, Lewtschenko T, Slack JP, Ward CD, Meyerhof W (2005). "Bitter taste receptors for saccharin and acesulfame K." J. Neurosci. 24 (45): 10260–5. doi:10.1523/JNEUROSCI.1225-04.2004. PMC 6730199. PMID 15537898.
Go Y, Satta Y, Takenaka O, Takahata N (2006). "Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates". Genetics. 170 (1): 313–26. doi:10.1534/genetics.104.037523. PMC 1449719. PMID 15744053.
Behrens M, Bartelt J, Reichling C, Winnig M, Kuhn C, Meyerhof W (2006). "Members of RTP and REEP gene families influence functional bitter taste receptor expression". J. Biol. Chem. 281 (29): 20650–9. doi:10.1074/jbc.M513637200. PMID 16720576.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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[refGRCh38Ensembl-1] ENSG00000262612, ENSG00000282537 GRCh38: Ensembl release 89: ENSG00000255374, ENSG00000262612, ENSG00000282537 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000053217 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12379855-5] Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (Oct 2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat Genet. 32 (3): 397–401. doi:10.1038/ng1014. PMID 12379855. S2CID 20426192.

[entrez-6] "Entrez Gene: TAS2R43 taste receptor, type 2, member 43".

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TAS2R43

See also

References

Further reading