Amaç: Ortak etiyolojik faktörler nedeni ile larinks ve akciğer maligniteleri, aynı hastada eş zam... more Amaç: Ortak etiyolojik faktörler nedeni ile larinks ve akciğer maligniteleri, aynı hastada eş zamanlı veya metakron olarak gelişebilmektedir. Çalışmamızda bu hastalara yönelik klinik yaklaşımlar ile tedavi protokollerimizi sunmayı amaçladık. Gereç ve Yöntem: Kliniğimizde Ocak 2010 Nisan 2016 yılları arasında, öncesinde larinks malignitesi tanısı alan ve akciğerde lezyon sebebi ile cerrahi uygulanan hastalar retrospektrif olarak incelendi. Bulgular: Çalışmaya dahil edilen, tamamı erkek 20 hastanın yaş ortalaması 62.18 2.65 (47-84) idi. Larinks malignitesi ile eş zamanlı olarak akciğerde lezyon saptanan ve henüz larinks malignitesine yönelik hiçbir tedavi almamış olan hastalar Grup (6 hasta), larinks malignitesine yönelik tedavilerini almakta olan veya tamamlayan, izlemde akciğer lezyonu saptanan hastalar ise Grup (14 hasta) olarak tanımlandı. Grup 2'deki hastalardan dördünde trakeostomi mevcuttu. Hastaların dördüne (%20) solunum fonksiyon testi (SFT) yapılamadı, üç hastada (%15) ...
Background: Although the etiology of primer spontaneous pneumothorax (PSP) is not exactly underst... more Background: Although the etiology of primer spontaneous pneumothorax (PSP) is not exactly understood, it has been suggested to be associated with rupture of bulla/bleb formations at the lung apices in thin, tall, young adults. In this study, we aim to evaluate whether delayed puberty is a new etiological factor for PSP. Materials and Methods: A total of 91 patients who were treated for PSP in our clinic between January 2013 and September 2016 and who were scheduled for a follow-up visit by phone call and underwent pubertal-stage assessment were retrospectively analyzed. Results: Of all patients, 10 (12.1%) were females and 81 (87.9%) were males. The mean age was 25.90 ± 6.83 (range, 17 to 38) years and the mean height was 178.90 ± 7.6 (range, 161 to 197) cm. The mean age at menarche of female patients was 14.20 ± 1.31 (range, 12 to 17) years. The women had a late age at menarche compared to the overall Turkish female population (p < 0.0001). The mean age for the development of facial hairs in the men was 16.63 ± 1.69 (range, 13 to 22) years, showing a later age, compared to the overall Turkish male population (p < 0.0001). Conclusion: Our study results showed that the patients with pneumothorax had an advanced age at puberty, compared to the normal overall population, and that the pubertal growth spurt occurred within a short period of time. This condition is also suggested to have an effect on the lung maturity and the development of pneumothorax.
A 73-year-old man underwent left pneumonectomy for squamous cell lung carcinoma 3 years ago. The ... more A 73-year-old man underwent left pneumonectomy for squamous cell lung carcinoma 3 years ago. The postoperative and follow-up periods were uneventful. A thrombus was detected in the left pulmonary artery stump during the last chest computed tomography (CT) scan. Anticoagulant treatment was applied: intravenous heparin for 3 days followed by oral warfarin. The follow-up chest CT examination revealed regression in the size of the thrombus.
Microabstract: Study investigated if there was a survival difference between sinN2 and mulN2 dise... more Microabstract: Study investigated if there was a survival difference between sinN2 and mulN2 disease in operated NSCLC patients. 73 patients had sinN2 and 38 patients had mulN2 disease. The median survival and the 5-year survival rate of sinN2 and mulN2 were 26 months and 20.5% against 20 months and 0%, respectively, and there was a statistically significant difference between two groups (0.032). Background: The most important parameter determining the treatment and survival in non-small cell lung cancer is the stage of the disease and the associated lymph node involvement. The present study investigated if there was a survival difference between single-station N2 (sinN2-Group 1) and multistation N2 (mulN2-Group 2) disease in operated non-small cell lung cancer (NSCLC) patients. Materials and methods: The patients, who were diagnosed with NSCLC and underwent anatomic resection and mediastinal lymph node dissection and found to have ipsilateral lymph node metastasis between January 2005 and December 2011 in our clinic, were investigated retrospectively. Results: 801 patients had anatomic resection. Among these patients, a total of 111 patients (13.8%) were found pathological N2 (þ). 73 (66.6%) patients had sinN2 and 38 (33.4%) patients had mulN2 disease. Out of these patients, 94 (85.4%) were male and 17 (14.6%) were female, and the mean age was 58.9710.2 (35-82) years. The median survival and the 5-year survival rate of sinN2 and mulN2 were 26 months and 20.5% against 20 months and 0%, respectively, and there was a statistically significant difference between two groups (0.032). Conclusions: TNM system used in the current lung cancer staging assesses only the localizations of the metastatic lymph node stations. However, it seems that the localization of the lymph node stations alone is not completely enough for an estimated survival. The present study has found poorer survival in the multi-station N2 patients than the single-station N2 patients, which is also statistically significant.
Objective: Protein-rich nutrition is necessary for wound healing after surgery. In this study, th... more Objective: Protein-rich nutrition is necessary for wound healing after surgery. In this study, the benefit of preoperative nutritional support was investigated for non-small cell lung cancer patients who underwent anatomic resection. Methods: A prospective study was planned with the approval of our institutional review board. Fifty-eight patients who underwent anatomic resection in our department between January 2014 and December 2014 were randomized. Thirty-one patients were applied a preoperative nutrition program with immune modulating formulae (enriched with arginine, omega-3 fatty acids and nucleotides) for ten days. There were 27 patients in the control group who were fed with only normal diet. Patients who were malnourished, diabetic or who had undergone bronchoplastic procedures or neoadjuvant therapy were excluded from the study. Patients' baseline serum albumin levels, defined as the serum albumin level before any nutrition program, and the serum albumin levels on the postoperative third day were calculated and recorded with the other data. Results: Anatomic resection was performed by thoracotomy in 20 patients, and 11 patients were operated by videothoracoscopy in the nutrition program group. On the other hand 16 patients were operated by thoracotomy and 11 patients were operated by videothoracoscopy in the control group. In the control group, the patients' albumin levels decreased to 25.71 % of the baseline on the postoperative third day, but this reduction was only 14.69 % for nutrition program group patients and the difference was statistically significant (p < 0.001). Complications developed in 12 patients (44.4 %) in the control group compared to 6 patients in the nutrition group (p = 0.049). The mean chest tube drainage time was 6 (1-42) days in the control group against 4 (2-15) days for the nutrition program group (p = 0.019). Conclusions: Our study showed that preoperative nutrition is beneficial in decreasing the complications and chest tube removal time in non-small cell lung cancer patients that were applied anatomic resection with a reduction of 25 % in the postoperative albumin levels of non-malnourished patients who underwent resection.
Open Access Research Journal of Science and Technology, 2021
Myxofibrosarcoma is a variant of fibrosarcoma, a tumor consisting of malignant fibroblasts, exhib... more Myxofibrosarcoma is a variant of fibrosarcoma, a tumor consisting of malignant fibroblasts, exhibiting a variable myxoid stroma, pleomorphism and wide curved vascular pattern. The most common location site of the tumor is the extremities. Uncommonly it is located in the trunk, head and neck. Herein we present a very rare case of surgically treated chest-wall-myxofibrosarcoma.
OBJECTIVE: Preoperative evaluation in thoracic surgery is highly important to determine surgical ... more OBJECTIVE: Preoperative evaluation in thoracic surgery is highly important to determine surgical suitability, estimate postoperative pulmonary complications, and for patient follow-up. However, there is neither a definite explanation about the possible complications nor a gold standard method. MATERIALS AND METHODS: In this study, 297 patients undergoing anatomic lung resection for primary lung carcinoma were retrospectively evaluated. To form a homogeneous group, all factors that increase the rate of pulmonary complication were excluded except emphysema. Patients who did not meet these criteria were removed from the study. The study continued with 104 other patients. This patient subgroup was divided into groups according to Goddard Classification– Score (GdCS). The correlation between GdCS and other variables was statistically investigated. RESULTS: According to the GdCS of 104 patients, the patient distribution was as follows: 10 patients (9.6%) were G0, 28 patients (26.9%) were G1, 42 patients (40.4%) were G2, 22 patients (21.2%) were G3, and 2 patients (1.9%) were G4. Thirty-five (33.6%) of 104 patients had a pulmonary complication during the postoperative follow-up. The average drainage time was longer for higher GdCS scores, and the rate of exposition to a pulmonary complication was higher in the patients with increased GdCS. CONCLUSION: In view of these findings, Goddard's scoring for chronic obstructive pulmonary disease-emphysema patients was considered likely to be an indicative parameter in the preoperative evaluation and postoperative follow-up of thoracic surgery patients.
Hidatidozis, cogunlukla kopek diskisi ile insana bulasan Echinococcus granulosus'un larva for... more Hidatidozis, cogunlukla kopek diskisi ile insana bulasan Echinococcus granulosus'un larva formlarinin neden oldugu paraziter bir hastaliktir. Hidatik kistlerin en sik yerlestigi organlar karaciger (%60-70) ve akcigerler (%20-30) olup intratorasik ekstrapulmoner tutulum nadirdir. Hastalarin semptomlari kistin yerlesim yerine ve buyuklugune gore degisiklik gostermektedir. Karaciger veya akciger operasyonu sonrasi nuks orani %1.4-%11 arasindadir. Bu yazida, 16 ve 20 yil once akciger kist hidatigi nedeniyle opere edilmis iki olguda gelisen intratorasik ekstraparankimal dev kist hidatiklerinin tani ve tedavisi degerlendirildi.
Amaç: Ortak etiyolojik faktörler nedeni ile larinks ve akciğer maligniteleri, aynı hastada eş zam... more Amaç: Ortak etiyolojik faktörler nedeni ile larinks ve akciğer maligniteleri, aynı hastada eş zamanlı veya metakron olarak gelişebilmektedir. Çalışmamızda bu hastalara yönelik klinik yaklaşımlar ile tedavi protokollerimizi sunmayı amaçladık. Gereç ve Yöntem: Kliniğimizde Ocak 2010 Nisan 2016 yılları arasında, öncesinde larinks malignitesi tanısı alan ve akciğerde lezyon sebebi ile cerrahi uygulanan hastalar retrospektrif olarak incelendi. Bulgular: Çalışmaya dahil edilen, tamamı erkek 20 hastanın yaş ortalaması 62.18 2.65 (47-84) idi. Larinks malignitesi ile eş zamanlı olarak akciğerde lezyon saptanan ve henüz larinks malignitesine yönelik hiçbir tedavi almamış olan hastalar Grup (6 hasta), larinks malignitesine yönelik tedavilerini almakta olan veya tamamlayan, izlemde akciğer lezyonu saptanan hastalar ise Grup (14 hasta) olarak tanımlandı. Grup 2'deki hastalardan dördünde trakeostomi mevcuttu. Hastaların dördüne (%20) solunum fonksiyon testi (SFT) yapılamadı, üç hastada (%15) ...
Background: Although the etiology of primer spontaneous pneumothorax (PSP) is not exactly underst... more Background: Although the etiology of primer spontaneous pneumothorax (PSP) is not exactly understood, it has been suggested to be associated with rupture of bulla/bleb formations at the lung apices in thin, tall, young adults. In this study, we aim to evaluate whether delayed puberty is a new etiological factor for PSP. Materials and Methods: A total of 91 patients who were treated for PSP in our clinic between January 2013 and September 2016 and who were scheduled for a follow-up visit by phone call and underwent pubertal-stage assessment were retrospectively analyzed. Results: Of all patients, 10 (12.1%) were females and 81 (87.9%) were males. The mean age was 25.90 ± 6.83 (range, 17 to 38) years and the mean height was 178.90 ± 7.6 (range, 161 to 197) cm. The mean age at menarche of female patients was 14.20 ± 1.31 (range, 12 to 17) years. The women had a late age at menarche compared to the overall Turkish female population (p < 0.0001). The mean age for the development of facial hairs in the men was 16.63 ± 1.69 (range, 13 to 22) years, showing a later age, compared to the overall Turkish male population (p < 0.0001). Conclusion: Our study results showed that the patients with pneumothorax had an advanced age at puberty, compared to the normal overall population, and that the pubertal growth spurt occurred within a short period of time. This condition is also suggested to have an effect on the lung maturity and the development of pneumothorax.
A 73-year-old man underwent left pneumonectomy for squamous cell lung carcinoma 3 years ago. The ... more A 73-year-old man underwent left pneumonectomy for squamous cell lung carcinoma 3 years ago. The postoperative and follow-up periods were uneventful. A thrombus was detected in the left pulmonary artery stump during the last chest computed tomography (CT) scan. Anticoagulant treatment was applied: intravenous heparin for 3 days followed by oral warfarin. The follow-up chest CT examination revealed regression in the size of the thrombus.
Microabstract: Study investigated if there was a survival difference between sinN2 and mulN2 dise... more Microabstract: Study investigated if there was a survival difference between sinN2 and mulN2 disease in operated NSCLC patients. 73 patients had sinN2 and 38 patients had mulN2 disease. The median survival and the 5-year survival rate of sinN2 and mulN2 were 26 months and 20.5% against 20 months and 0%, respectively, and there was a statistically significant difference between two groups (0.032). Background: The most important parameter determining the treatment and survival in non-small cell lung cancer is the stage of the disease and the associated lymph node involvement. The present study investigated if there was a survival difference between single-station N2 (sinN2-Group 1) and multistation N2 (mulN2-Group 2) disease in operated non-small cell lung cancer (NSCLC) patients. Materials and methods: The patients, who were diagnosed with NSCLC and underwent anatomic resection and mediastinal lymph node dissection and found to have ipsilateral lymph node metastasis between January 2005 and December 2011 in our clinic, were investigated retrospectively. Results: 801 patients had anatomic resection. Among these patients, a total of 111 patients (13.8%) were found pathological N2 (þ). 73 (66.6%) patients had sinN2 and 38 (33.4%) patients had mulN2 disease. Out of these patients, 94 (85.4%) were male and 17 (14.6%) were female, and the mean age was 58.9710.2 (35-82) years. The median survival and the 5-year survival rate of sinN2 and mulN2 were 26 months and 20.5% against 20 months and 0%, respectively, and there was a statistically significant difference between two groups (0.032). Conclusions: TNM system used in the current lung cancer staging assesses only the localizations of the metastatic lymph node stations. However, it seems that the localization of the lymph node stations alone is not completely enough for an estimated survival. The present study has found poorer survival in the multi-station N2 patients than the single-station N2 patients, which is also statistically significant.
Objective: Protein-rich nutrition is necessary for wound healing after surgery. In this study, th... more Objective: Protein-rich nutrition is necessary for wound healing after surgery. In this study, the benefit of preoperative nutritional support was investigated for non-small cell lung cancer patients who underwent anatomic resection. Methods: A prospective study was planned with the approval of our institutional review board. Fifty-eight patients who underwent anatomic resection in our department between January 2014 and December 2014 were randomized. Thirty-one patients were applied a preoperative nutrition program with immune modulating formulae (enriched with arginine, omega-3 fatty acids and nucleotides) for ten days. There were 27 patients in the control group who were fed with only normal diet. Patients who were malnourished, diabetic or who had undergone bronchoplastic procedures or neoadjuvant therapy were excluded from the study. Patients' baseline serum albumin levels, defined as the serum albumin level before any nutrition program, and the serum albumin levels on the postoperative third day were calculated and recorded with the other data. Results: Anatomic resection was performed by thoracotomy in 20 patients, and 11 patients were operated by videothoracoscopy in the nutrition program group. On the other hand 16 patients were operated by thoracotomy and 11 patients were operated by videothoracoscopy in the control group. In the control group, the patients' albumin levels decreased to 25.71 % of the baseline on the postoperative third day, but this reduction was only 14.69 % for nutrition program group patients and the difference was statistically significant (p < 0.001). Complications developed in 12 patients (44.4 %) in the control group compared to 6 patients in the nutrition group (p = 0.049). The mean chest tube drainage time was 6 (1-42) days in the control group against 4 (2-15) days for the nutrition program group (p = 0.019). Conclusions: Our study showed that preoperative nutrition is beneficial in decreasing the complications and chest tube removal time in non-small cell lung cancer patients that were applied anatomic resection with a reduction of 25 % in the postoperative albumin levels of non-malnourished patients who underwent resection.
Open Access Research Journal of Science and Technology, 2021
Myxofibrosarcoma is a variant of fibrosarcoma, a tumor consisting of malignant fibroblasts, exhib... more Myxofibrosarcoma is a variant of fibrosarcoma, a tumor consisting of malignant fibroblasts, exhibiting a variable myxoid stroma, pleomorphism and wide curved vascular pattern. The most common location site of the tumor is the extremities. Uncommonly it is located in the trunk, head and neck. Herein we present a very rare case of surgically treated chest-wall-myxofibrosarcoma.
OBJECTIVE: Preoperative evaluation in thoracic surgery is highly important to determine surgical ... more OBJECTIVE: Preoperative evaluation in thoracic surgery is highly important to determine surgical suitability, estimate postoperative pulmonary complications, and for patient follow-up. However, there is neither a definite explanation about the possible complications nor a gold standard method. MATERIALS AND METHODS: In this study, 297 patients undergoing anatomic lung resection for primary lung carcinoma were retrospectively evaluated. To form a homogeneous group, all factors that increase the rate of pulmonary complication were excluded except emphysema. Patients who did not meet these criteria were removed from the study. The study continued with 104 other patients. This patient subgroup was divided into groups according to Goddard Classification– Score (GdCS). The correlation between GdCS and other variables was statistically investigated. RESULTS: According to the GdCS of 104 patients, the patient distribution was as follows: 10 patients (9.6%) were G0, 28 patients (26.9%) were G1, 42 patients (40.4%) were G2, 22 patients (21.2%) were G3, and 2 patients (1.9%) were G4. Thirty-five (33.6%) of 104 patients had a pulmonary complication during the postoperative follow-up. The average drainage time was longer for higher GdCS scores, and the rate of exposition to a pulmonary complication was higher in the patients with increased GdCS. CONCLUSION: In view of these findings, Goddard's scoring for chronic obstructive pulmonary disease-emphysema patients was considered likely to be an indicative parameter in the preoperative evaluation and postoperative follow-up of thoracic surgery patients.
Hidatidozis, cogunlukla kopek diskisi ile insana bulasan Echinococcus granulosus'un larva for... more Hidatidozis, cogunlukla kopek diskisi ile insana bulasan Echinococcus granulosus'un larva formlarinin neden oldugu paraziter bir hastaliktir. Hidatik kistlerin en sik yerlestigi organlar karaciger (%60-70) ve akcigerler (%20-30) olup intratorasik ekstrapulmoner tutulum nadirdir. Hastalarin semptomlari kistin yerlesim yerine ve buyuklugune gore degisiklik gostermektedir. Karaciger veya akciger operasyonu sonrasi nuks orani %1.4-%11 arasindadir. Bu yazida, 16 ve 20 yil once akciger kist hidatigi nedeniyle opere edilmis iki olguda gelisen intratorasik ekstraparankimal dev kist hidatiklerinin tani ve tedavisi degerlendirildi.
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