Papers by Xanthoula Atsalaki
High-throughput technologies, such as chromatin immunoprecipitation (ChIP) with massively paralle... more High-throughput technologies, such as chromatin immunoprecipitation (ChIP) with massively parallel sequencing (ChIPseq) have enabled cost and time efficient generation of immense amount of genome data. The advent of advanced sequencing techniques allowed biologists and bioinformaticians to investigate biological aspects of cell function and understand or reveal unexplored disease etiologies. Systems biology attempts to formulate the molecular mechanisms in mathematical models and one of the most important areas is the gene regulatory networks (GRNs), a collection of DNA segments that somehow interact with each other. GRNs incorporate valuable information about molecular targets that can be corellated to specific phenotype.
High-throughput technologies, such as chromatin immunoprecipitation (ChIP) with massively paralle... more High-throughput technologies, such as chromatin immunoprecipitation (ChIP) with massively parallel sequencing (ChIP-seq) have enabled cost and time efficient generation of immense amount of genome data. The advent of advanced sequencing techniques allowed biologists and bioinformaticians to investigate biological aspects of cell function and understand or reveal unexplored disease etiologies. Systems biology attempts to formulate the molecular mechanisms in mathematical models and one of the most important areas is the gene regulatory networks (GRNs), a collection of DNA segments that somehow interact with each other. GRNs incorporate valuable information about molecular targets that can be corellated to specific phenotype.In our study we highlight the need to develop new explorative tools and approaches for the integration of different types of -omics data such as ChIP-seq and GRNs using pathway analysis methodologies. We present an integrative approach for ChIP-seq and gene expres...
International Journal of Semantic Computing, 2016
The advent of new web technologies and the explosion of available information online led to an in... more The advent of new web technologies and the explosion of available information online led to an information overload. During this information revolution blogs have become considerably mainstream as a media of providing news. Although there are several arguments about their validity and credibility the large amount of blogs currently available require the usage of advanced techniques for the collection, analysis, mining and efficient querying of the available information. To this direction we present BlogSearch, a novel platform allowing aggregating, indexing and searching blog articles. The information is modelled using a novel RDF/S Ontology named Blogs Ontology and published as Linked Open Data. In addition, two sets of APIs are provided for inserting, updating and searching information whereas the platform provides also graphical user interfaces (GUIs) for searching and inserting information. To the best of our knowledge our platform is the only one currently available publishing ...
Τα τελευταία χρόνια είμαστε όλοι μάρτυρες τεχνολογικών επιτευγμάτων που έχουν κατακλύσει την καθη... more Τα τελευταία χρόνια είμαστε όλοι μάρτυρες τεχνολογικών επιτευγμάτων που έχουν κατακλύσει την καθημερινότητα μας. Τα σχολεία μας κατακλύζονται και αυτά από πλήθος τεχνολογικών εφαρμογών στο όνομα της δημιουργίας ενός αποτελεσματικότερου και παιδαγωγικότερου περιβάλλοντος μάθησης και διδασκαλίας. Ένα από τα πλέον πρόσφατα επιτεύγματα της τεχνολογίας που βρίσκεται στη διάθεση των εκπαιδευτικών και γενικότερα της εκπαίδευσης είναι ο διαδραστικός πίνακας αφής(interactive whiteboard), ένα αρκετά αμφιλεγόμενο εργαλείο που έχουν στα χέρια τους οι εκπαιδευτικοί της «παλαιάς κοπής» αλλά και οι «νέοι» εκπαιδευτικοί(Αναστασιάδης Π. 2010). Ο τρόπος γενικότερα με τον οποίο χρησιμοποιείται η τεχνολογία στην σχολική τάξη προκαλεί αρκετούς προβληματισμούς καθώς πολλές φορές δίνεται μικρότερη σημασία στις παιδαγωγικές μεθόδους που θα χρησιμοποιηθούν και μεγαλύτερη έμφαση στα τεχνολογικά μέσα και πόρους. «Μια καλή διδασκαλία θα μπορούσε να αντισταθμίσει την έλλειψη τεχνολογικών μέσων, αλλά η τεχνολογί...
Uploads
Papers by Xanthoula Atsalaki