Teaching Documents by Moisés Canle
Papers by Moisés Canle
Journal of Cleaner Production, Oct 31, 2023
Journal of the Chemical Society, 1993
ABSTRACT The decomposition of the N-Cl and N-Br derivatives of L-glycine and L-sarcosine in alkal... more ABSTRACT The decomposition of the N-Cl and N-Br derivatives of L-glycine and L-sarcosine in alkaline medium shows a first-order dependence, with respect to the N-halo-α-amino acid and to the concentration of hydroxide ions. From the leaving group effect and the primary deuterium kinetic isotope effect, and in the framework of the principle of non-perfect synchronization, the conclusion can be drawn that the decomposition of the N-halo-α-amino acids in alkaline medium can be satisfactorily described through an (AxhDHDN) mechanism with a carbanion and reactant-like transition state.
Applied Clay Science, Dec 1, 2018
Environments, Feb 23, 2023
This article is an open access article distributed under the terms and conditions of the Creative... more This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY
Acta Crystallographica Section E-structure Reports Online, Jul 17, 2003
ABSTRACT In the title molecule, C18H18O5, the cyclohexene ring adopts an envelope conformation. T... more ABSTRACT In the title molecule, C18H18O5, the cyclohexene ring adopts an envelope conformation. The dihedral angle between the two furan rings is 65.9 (1) degrees. In the crystal structure, the carboxyl groups of inversion-related moleules are involved in the formation of dimers through O-H...O hydrogen bonds.
Journal of Physical Organic Chemistry, May 27, 2016
An entry from the Cambridge Structural Database, the world's repository for small molecule cr... more An entry from the Cambridge Structural Database, the world's repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
An entry from the Cambridge Structural Database, the world's repository for small molecule cr... more An entry from the Cambridge Structural Database, the world's repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
An entry from the Cambridge Structural Database, the world's repository for small molecule cr... more An entry from the Cambridge Structural Database, the world's repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
An entry from the Cambridge Structural Database, the world's repository for small molecule cr... more An entry from the Cambridge Structural Database, the world's repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
Journal of Physical Organic Chemistry, Aug 31, 2017
We have studied the mechanism of solvolysis of arenesulfonyl chlorides by propan-1-ol and propan-... more We have studied the mechanism of solvolysis of arenesulfonyl chlorides by propan-1-ol and propan-2-ol at 303-323 K. Kinetic profiles were appropriately fit by first-order kinetics. Reactivity increases with electron-donating substituents. Ortho-alkyl substituted derivatives of arenesulfonyl chlorides show increased reactivity, but the origin of this “positive” ortho-effect remains unclear. Likely, ortho-methyl groups restrict rotation around the C-S bond, facilitating the attack of the nucleophile. No relevant reactivity changes have been found with propan-1-ol and propan-2-ol in terms of nucleophile steric effect. The existence of isokinetic relationships for all substrates suggests a single mechanism for the series. Solvolysis reactions of all substrates in both alcohols show isokinetic temperatures (Tiso) close to the working temperature range, which is an evidence of the process being influenced by secondary reactivity factors, likely of steric nature in the TS. Solvation plays a relevant role in this reaction, modulating the reactivity. In some cases, the presence of t-Bu instead of Me in para- position leads to changes in the first solvation shell, increasing the energy of the reaction (ca. 1 kJ·mol−1). The obtained results suggest the same kinetic mechanism of solvolysis of arenesulfonyl chlorides for propan-1-ol and propan-2-ol, as in MeOH and EtOH, where bimolecular nucleophilic substitution (SN2) takes place with nucleophilic solvent assistance of one alcohol molecule and the participation of the solvent network involving solvent molecules of the first solvation shell.
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Teaching Documents by Moisés Canle
Papers by Moisés Canle