File:Fetale hematopoese.png

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Fetale_hematopoese.png (593 × 570 pixels, file size: 27 KB, MIME type: image/png)

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Deutsch: Aufenthaltsorte von hämatopoetischen Stammzellen während der embryonalen Entwicklung bei der Maus. Eine geringe Anzahl von Stammzellen hält sich jeweils im Blut auf, über das die Zellen von einer Stammzellnische zur nächsten wandern können. Die große Abnahme der Zahl der Stammzellen in der Leber ist vermutlich auf eine Differnzierung in verschiedene Blutzellen zurückzuführen.
English: Original figure Legend:

Figure 6.An Updated Model Illustrating the Location and Relative Frequencies of Fetal HSCs in the Embryo. HSCs are found constitutively at low numbers in fetal blood following the onset of circulation. Seeding of developing hematopoietic tissues by long-term HSCs is gradual and is not due to a large influx of cells. The large decline in HSC numbers seen in the fetal liver following 14 dpc is most likely the result of differentiation signaled by the developing hepatic environment rather than a timed migration to the fetal spleen and bone marrow.

HSCs are hematopoietic stem cells. This diagram shows the situation in the mouse embryo.
Date
Source Christensen JL, Wright DE, Wagers AJ, Weissman IL (March 2004). "Circulation and chemotaxis of fetal hematopoietic stem cells". PLoS biology 2 (3): E75. DOI:10.1371/journal.pbio.0020075. PMID 15024423. PMC: 368169.
Author Christensen JL, Wright DE, Wagers AJ, Weissman IL.
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current15:58, 2 November 2008Thumbnail for version as of 15:58, 2 November 2008593 × 570 (27 KB)Dietzel65 (talk | contribs)== Beschreibung == {{Information |Description={{en|1=Original figure Legend: '' Figure 6.An Updated Model Illustrating the Location and Relative Frequencies of Fetal HSCs in the Embryo. HSCs are found constitutively at low numbers in fetal blood followin

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