File:Embryonic myogenesis mouse.jpg
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| Description | Embryonic myogenesis (A) Schematic representation of somite maturation. Somites mature following an anterior to posterior developmental gradient (Modified from Gray's Anatomy. The Anatomical Basis of Clinical Practice, 40th Edition Standring, 2008): myogenic precursor cells arise from the epaxial and hypaxial lips of the dermomyotome after archive epithelial-mesenchymal transition (EMT) and migrate toward the limbs to form dorsal and ventral muscle masses where they begin to differentiate. (B,C) Head frontal and transverse planes of a mouse embryo between stages of development E7.5–8.75 and E8–9.25 in mouse. At an open neural plate stage, head mesoderm in a frontal plane includes the prechordal mesoderm and the paraxial mesoderm. When the neural tube closes dorsally and the endoderm ventrally, the prechordal mesoderm is integrated within the remaining paraxial mesoderm, which is located anterior to the somites. Dashed line illustrates the cutting plane. (D) Origins of skeletal muscles: Myogenic precursors arise from different paraxial mesoderm compartments. (E) Pitx2 expression domains at the E10.5 stage of development in mouse. NT, neural tube; NC, notochord; SM, somites; DMT, dermomyotome; ST, sclerotome; MT, myotome; LMP, limb muscle precursors; FL, forelimb; PAM, head paraxial mesoderm; PCM, prechordal mesoderm; PROS, prosencephalon; MES, mesencephalon; MET, metencephalon; SPM, splanchnic mesoderm; OFT, outflow tract of heart; HT, heart tube; EOM, extra-ocular muscles; BRM, branchial muscles; LGM, laryngoglossal muscles; HGC, hypoglossal cord; ANM, axial neck muscles; BM, back muscles; BWM, body wall muscles; FLM, forelimbs muscles; HLM, hind limbs muscles. |
| Source | https://www.researchgate.net/figure/Embryonic-myogenesis-A-Schematic-representation-of-somite-maturation-Somites-mature_fig1_316608183 https://www.researchgate.net/publication/316608183_Pitx2_in_Embryonic_and_Adult_Myogenesis Pitx2 in Embryonic and Adult Myogenesis, May 2017, Frontiers in Cell and Developmental Biology, 5, DOI:10.3389/fcell.2017.00046 |
| Author | Amelia E Aránega, Universidad de Jaén, Francisco Hernández-Torres, Universidad de Jaén, Lara Rodríguez-Outeiriño, University of Galway, Diego Franco, Universidad de Jaén |
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| current | 09:43, 23 April 2024 | | 1,261 × 1,278 (938 KB) | Rasbak (talk | contribs) | {{Information |description= Embryonic myogenesis (A) Schematic representation of somite maturation. Somites mature following an anterior to posterior developmental gradient (Modified from Gray's Anatomy. The Anatomical Basis of Clinical Practice, 40th Edition Standring, 2008): myogenic precursor cells arise from the epaxial and hypaxial lips of the dermomyotome after archive epithelial-mesenchymal transition (EMT) and migrate toward the limbs to form dorsal and ventral muscle masses where the... |
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