File:Dorsal lip transplantation in a salamander embryo.png
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Dorsal lip transplantation in a salamander embryo
Summary
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English: For her PhD thesis, Hilde Mangold, the German embryologist who worked with Hans Spemann, picked a minuscule tissue sample out of the egg of a pigmented salamander, not even the size of a pinprick, and inoculated it onto another white salamander embryo. She didn’t just take a random piece of tissue. She took a very small region, which Spemann believed to be the location of those cells that were forming the major part of the three germ layers. The figure shows transverse sections of blastula, gastrula and neurula with the transplanted lip and thus with the two neural tubes as well as the resulting conjoined twins.
Nederlands: Voor haar proefschrift haalde Hilde Mangold, de Duitse embryoloog die samenwerkte met Hans Spemann, een minuscuul stukje weefsel weg uit het ei van een gepigmenteerde salamander. Dit stukje dat ongeveer zo groot was als een speldenknop, plaatste ze in een ander salamander embryo die niet gepigmenteerd was. Ze nam niet zomaar een willekeurig stukje weefsel. Ze nam een heel klein gebied, waarvan Spemann dacht dat het de locatie was van de cellen die het grootste deel van de drie kiemlagen vormden. In de figuur zijn transversale doorsneden te zien van blastula, gastrula en neurula met de getransplanteerde lip en dus met de twee neurale buizen evenals de resulterende Siamese tweeling. |
| Date | |
| Source | VAN Robays J. Hilde Mangold-Pröscholdt (1898 - 1924): The Spemann-Mangold Organizer. Facts Views Vis Obgyn. 2016 Mar 28;8(1):63-68. PMID: 27822353; PMCID: PMC5096429. |
| Author | J. Van Robays |
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