The increase level of serum phosphate is common due to secretion failure of the kidney on chronic... more The increase level of serum phosphate is common due to secretion failure of the kidney on chronic kidney disease patients (CKD). The study objective is to determine the level of serum phosphate among the CKD patient on chronic dialysis in Gianyar Bali. A prospective cross-sectional study conducted in 100 serum of the patients visiting dialysis clinic in Sanjiwani and Arisanti Hospital on October 2018. A three mL of blood was collected and the phosphate level was measured with spectrophotometer. Sixty-seven of 100 samples was male with mean age of 52.52 (SD±12.811). The most cause of CKD was chronic pyelonephritis. The mean of hemodialysis duration was 44.59 (SD± 32.40). Level of the phosphate more than normal limit found as high as 69% of the samples. There was a correlation between age (p=0.001), gender (p=0.020) and phosphate level, but no correlation between Body Mass Index, hemodialysis duration and phosphate level were observed, accounting for p=0.222 and p=0.264, respectively. High finding of hyperphosphatemia that found in the study revealed the presentation of CKDmineral and bone disorder in CKD patients. Correlation of age with higher phosphate level may relate with the deterioration of kidney function in elderly.
BACKGROUND: Neopterin is a soluble biomarker of monocyte activation and its increased concentrati... more BACKGROUND: Neopterin is a soluble biomarker of monocyte activation and its increased concentration might be expressed in atherosclerosis. Until recently, there has been lacking of information on the prognostic role of neopterin in acute coronary syndromes (ACS). The study was aimed at measuring the associations between elevated serum neopterin and increased risk of cardiovascular (CV) events in ACS.METHODS: This was a prospective cohort study, recruited 71 ACS patients from January 31 through August 31, 2007 in Sanglah Hospital of Udayana School of Medicine, Denpasar – Bali. Cardiovascular events, such as: CV death, recurrent myocardial infarction, stroke and recurrent myocardial ischemia were previously defined. Relative risk and survival rate were measured successively by Cox proportional model and Kaplan-Meier curve.RESULTS: Of 71 ACS patients aged 56.8 ± 9.5 years, 21 (29.5%) subjects underwent CV events. Overall mean followup was 151.6 (95% CI: 129.7 – 173.5) days. Baseline ch...
The increase level of serum phosphate is common due to secretion failure of the kidney on chronic... more The increase level of serum phosphate is common due to secretion failure of the kidney on chronic kidney disease patients (CKD). The study objective is to determine the level of serum phosphate among the CKD patient on chronic dialysis in Gianyar Bali. A prospective cross-sectional study conducted in 100 serum of the patients visiting dialysis clinic in Sanjiwani and Arisanti Hospital on October 2018. A three mL of blood was collected and the phosphate level was measured with spectrophotometer. Sixty-seven of 100 samples was male with mean age of 52.52 (SD±12.811). The most cause of CKD was chronic pyelonephritis. The mean of hemodialysis duration was 44.59 (SD± 32.40). Level of the phosphate more than normal limit found as high as 69% of the samples. There was a correlation between age (p=0.001), gender (p=0.020) and phosphate level, but no correlation between Body Mass Index, hemodialysis duration and phosphate level were observed, accounting for p=0.222 and p=0.264, respectively. High finding of hyperphosphatemia that found in the study revealed the presentation of CKDmineral and bone disorder in CKD patients. Correlation of age with higher phosphate level may relate with the deterioration of kidney function in elderly.
BACKGROUND: Neopterin is a soluble biomarker of monocyte activation and its increased concentrati... more BACKGROUND: Neopterin is a soluble biomarker of monocyte activation and its increased concentration might be expressed in atherosclerosis. Until recently, there has been lacking of information on the prognostic role of neopterin in acute coronary syndromes (ACS). The study was aimed at measuring the associations between elevated serum neopterin and increased risk of cardiovascular (CV) events in ACS.METHODS: This was a prospective cohort study, recruited 71 ACS patients from January 31 through August 31, 2007 in Sanglah Hospital of Udayana School of Medicine, Denpasar – Bali. Cardiovascular events, such as: CV death, recurrent myocardial infarction, stroke and recurrent myocardial ischemia were previously defined. Relative risk and survival rate were measured successively by Cox proportional model and Kaplan-Meier curve.RESULTS: Of 71 ACS patients aged 56.8 ± 9.5 years, 21 (29.5%) subjects underwent CV events. Overall mean followup was 151.6 (95% CI: 129.7 – 173.5) days. Baseline ch...
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